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Enroll in a Study.

Advances in understanding autism and related disorders are only possible as a direct result of the participation of individuals and families.

However, finding study participants is one of the greatest challenges researchers face. Simply put – scientists cannot make real progress without your help. We need you!

Studies Currently Enrolling:


autismMatch is an online registry that can quickly and easily connect interested individuals and families with research opportunities to advance scientists' understanding of ASD and related disorders, such as ADHD, anxiety, 22q deletion syndrome, and others.

Enroll here to be matched with studies tailored to your profile, and help researchers to understand the causes, characteristics, effective interventions, and access to support services for ASD and related disorders.

For more information:
Kathryn Lowe

Children's Autism Metabolome Project (CAMP)

The purpose of this study is to identify molecules in the blood and/or urine that differentiate children with Autism Spectrum Disorder (ASD) from children with delayed development (DD) and/or typical development (TD). These results may be used to develop a diagnostic decision tool in the future and will help researchers better understand genetic and metabolic conditions that affect some people with ASD. Potential subjects will be asked to give a sample of blood and urine (if able), and their parents will be asked to complete some questionnaires about medical history, development, and behavior. Participants will also be evaluated by an autism specialist and complete developmental and behavioral assessments during their clinical evaluation.

Click here for more information

For more information:
Vaikunt Ranganathan

Infant Brain Imaging Study (IBIS)

The goal of this research study is to improve the early detection of autism spectrum disorder (ASD) by following infants age 3-6 months who have an older sibling. Older siblings can be typically developing or have a diagnosis of ASD. This study conducts MRI (Magnetic Resonance Imaging) brain scan of children at risk for autism at around 12 months and again at around 24 months of age.

For more information:

Social-Motor Functioning in ASD

The goal of this research study is to create an index of movement and language abilities in children, teens, and adults- similar to the height and weight index that pediatricians use. Children and adults ages 2-89 with or  without ASD are invited to participate in this study, which involves a visit to CAR to complete a short questionnaire and 20 minutes of game-like activities designed to be fun.

For more information:
Emily Ferguson
infant in diaper

Infant Brain Development Study (MEG)

The goal of this study is to understand how brain processes change during child development. Infants between the ages of 6 to 12 months are eligible for a non-invasive brain imaging study specially developed for infants and toddlers to understand how brain processes change during child development. We will eventually use this information to better understand brain processes in children with neurodevelopmental disorders such as autism.

For more information:
smiling adolescent girl leaning on a tree

Measuring Anxiety in Autism Spectrum Disorder

This research study will help CAR researchers learn more about anxiety symptoms in autism spectrum disorder (ASD). Children aged 5-17 who have ASD and symptoms of anxiety- and their parents- are invited to participate in this study, which includes behavioral testing, heart rate measurements, and parent interviews.  There are a total of 1-3 study visits to the Center for Autism Research at CHOP, with a total time commitment of about 7 hours. Families will be compensated for their time and will receive a brief report of the results of the behavioral testing.

For more information:
Alisa Zoltowski
Help lead the way

Parents and providers needed for interview study: Using MEG Technology with Children with ASD

We are seeking parents, teachers & therapists familiar with ASD to help us prepare for an imaging study for minimally & nonverbal children. In the past, these children have been excluded from brain imaging studies. We would like to change this by using magnetoenchephalography (MEG) technology. We would like to interview parents, therapists, and teachers to help us design future MEG studies for children with ASD.

For more information:
Emily Kuschner, PhD

Research on Autism and Developmental Disorders (ROADD)

This research study will observe young children to learn more about the differences in social cognition and brain function that may be present in ASD.  We will use newly developed assessment tools like eye tracking and EEG technology to measure social processing and brain activity. Young children between the ages of 2 years and 5 years of age may enroll. We need children who have been previously diagnosed with an ASD as well as those who seem to be developing typically to take part. 

For more information:
Meredith Cola
Father daughter


SPARK (Simons Foundation Powering Autism Research for Knowledge) is a national autism research initiative open to individuals of all ages with a professional diagnosis of ASD living in the United States. ASD includes Asperger syndrome, autism/autistic disorder and pervasive developmental disorder-not otherwise specified (PDD-NOS). Participants are welcome to invite biological parents and full biological siblings (with and without ASD) to participate as well.

To learn more about SPARK and register online, visit www.SPARKforAutism.org/CHOP

For more information:
Lindsey DeMarco
Caucasian boy

Speech & Language Processing in Minimally & Non-Verbal Children

The goal of this study is to understand how children with little or no speech understand sounds and words. This study is enrolling boys and girls ages 8-12 who have ASD and are minimally verbal or nonverbal OR have a Developmental or Intellectual Disability (DD/ID).  What we learn from this study may help other people who have little or no speech. You will also receive a short report summarizing your child’s language and problem-solving skills.

For more information:
Virginia Burleson

Study of Brain Structure & Function in Teens

The goal of this study is to learn about brain function and structure in typically developing teens and in teens with Autism Spectrum Disorder (ASD). Teenaged boys and girls ages 12-16 with AND without ASD are eligible for this study to understand how brain processes change during child development.

For more information:
Leah Gaetz

Adults Needed for Social Communication Study

The goal of this research study is to learn how typically developing adults vary in their social communication skills and body movements from adults with autism spectrum disorder. For this study, we are recruiting adults with autism spectrum disorder as well as typically developing adults. Participation in the study involves two visits to CAR, spaced a few months apart. Study visits will include interviews and questionnaires to assess social understanding and social skills, and activities designed to measure motor behavior and communication in adults.

For more information:
Emily Ferguson
Teddy bear

Clinical Trial for Adolescents with 22q11.2DS and Attention Deficit Hyperactivity Disorder, Anxiety Disorder, and/or Autism Spectrum Disorder

The Children’s Hospital of Philadelphia is currently looking for 12 to 17 year olds with 22q11.2DS to participate in a Medgenics-sponsored research study testing an investigational medication for 22q11.2DS and Attention Deficit Hyperactivity Disorder, Anxiety Disorder, and/or Autism Spectrum Disorder.

For more information:

Longitudinal Study of Brain Development in School-Aged Children

The goal of this study is to understand  how brain structure & function change during childhood. Children aged 6-8 with or  without ASD are invited to participate in this study, which will involve two visits to CHOP about every 18 months for 3 years. We will have your child do tests of language, problem-solving, and basic academic skills as well as non-invasive (safe) brain imaging.

For more information:
Emma McBride
Caucasian boy

Study of How the Brain Processes Information

The goal of this research study ist to understand how children with and without ASD process information. Boys ages 6-17 with or without ASD are eligible to enroll in this 2-part study.

For more information:
Jennifer Jang

Study to Develop a Smartphone App

We are seeking parents of young children for this study to test a new research app for Android and iOS smartphones that measures how well a child responds to his or her name in everyday environments.  Children who don’t consistently recognize their name may have a developmental concern.  For this study, parents of any child between the ages of 18 months to 4 years are eligible (developmental concerns are not required). This study can be completed online or by phone. The total time commitment is about 4 hours over 4 weeks.

For more information:
Rebecca Thomas
Boy with basketball

Studying How the Brain Responds to Arbaclofen

This study for boys with ASD, aged 14 to 17 is meant to determine whether a single dose of the investigational drug Arbaclofen (STX-209) changes brain activity during a series of problem-solving activities.


To measure brain activity, we use a sort of helmet called magnetoencephalography (MEG), which is non-invasive and senses the brain's magnetic activity. The study involves 4 visits to CHOP.

For more information:
Virginia Burleson