Intervention Research & Clinical Trials

CHOP and Floreo Awarded $1.7M NIH Grant to Test Whether VR can Improve Police Safety in Individuals with ASD

The Small Business Technology Transfer Fast-track award will fund new pilots with Children’s Hospital of Philadelphia’s Center for Autism Research. ...

Social Anxiety, or Just Disinterested? (And Why it Matters.)

Social interactions are a common cause of anxiety among individuals with autism. However, it can be extremely challenging for parents or clinicians to distinguish between social disinterest and social anxiety in someone diagnosed with ASD. ...

Excess Brain Fluid May Be Early Indicator of Autism in Infants

A research team from The Children's Hospital of Philadelphia's Center for Autism Research (CAR) and colleagues from a national collaboration have made another discovery about the development of the brain in babies and toddlers who go onto have autism ...

New CHOP Research Study Tests Brain’s Response to Single Dose of Arbaclofen (STX209)

Many in the autism community are familiar with the trial drug STX209, also called arbaclofen, which affects a chemical system called GABA. In 2010, clinical trials were launched to evaluate whether arbaclofen might become the first medication to treat core symptoms of social communication impairment and repetitive behavior in autism spectrum disorder. ...

CHOP Researchers Identify Gene That Plays Important Role in Autism & Other Neuropsychiatric Conditions

A team of researchers led by Tara Wenger, PhD of The Children's Hospital of Philadelphia's Center for Autism Research (CAR) have found that genetic mutations in a specific family of genes – the “metabotropic glutamate receptors” (mGluRs) – play a significant role in a person’s risk for autism spectrum disorder (ASD)....

New Findings Related to Attention and Gaze Give Us Clues to Differences in Social Development for Individuals on the Autism Spectrum

Difficulty interpreting social information is one of the defining characteristics of autism spectrum disorders (ASD), but  there is still a lot we don't understand about the underlying causes of some of these social differences. ...

CAR Research: Attention and Gaze Hold Clues to Social Development in Autism

CAR psychologist Benjamin Yerys, PhD, studies attention, impulsivity, and distractibility in ASD, as well as in ADHD and anxiety- ASD’s frequent companions. A pair of his studies contribute to our understanding of how children with ASD prioritize and respond to social information in their environment. ...

Factors Associated with Driving in Teens with Autism Spectrum Disorder

Getting a permit and learning to drive is a ‘rite of passage’ that many teens anticipate for years. A driver’s license comes with independence and responsibility, which can be simultaneously exciting and intimidating. For teens with Autism Spectrum Disorder (ASD), the decision to learn to drive is met with additional challenges and considerations....

Twenty-Year Outcome for Individuals with ASD

Past research on adults diagnosed with Autism Spectrum Disorder (ASD) with average or near-average IQ scores have found a great variability in their outcomes (job, living independently, and friendships). To learn more about these outcomes, researchers interviewed the parents of adults with ASD who had participated in a study twenty years earlier. ...