The Accuracy of the ADOS-2 in Identifying Autism among Adults with Complex Psychiatric Conditions.

TitleThe Accuracy of the ADOS-2 in Identifying Autism among Adults with Complex Psychiatric Conditions.
Publication TypeJournal Article
Year of Publication2017
AuthorsMaddox, BB, Brodkin, ES, Calkins, ME, Shea, K, Mullan, K, Hostager, J, Mandell, DS, Miller, JS
JournalJ Autism Dev Disord
Volume47
Issue9
Pagination2703-2709
Date Published2017 Sep
ISSN1573-3432
Abstract

The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), Module 4 is considered a "gold-standard" instrument for diagnosing autism spectrum disorder (ASD) in adults. Although the ADOS-2 shows good sensitivity and specificity in lab-based settings, it is unknown whether these results hold in community clinics that serve a more psychiatrically impaired population. This study is the first to evaluate the diagnostic accuracy of the ADOS-2 among adults in community mental health centers (n = 75). The ADOS-2 accurately identified all adults with ASD; however, it also had a high rate of false positives among adults with psychosis (30%). Findings serve as a reminder that social communication difficulties measured by the ADOS-2 are not specific to ASD, particularly in clinically complex settings.

DOI10.1007/s10803-017-3188-z
Alternate JournalJ Autism Dev Disord
PubMed ID28589494
PubMed Central IDPMC5813679
Grant ListF32 MH111166 / MH / NIMH NIH HHS / United States
R34 MH100356 / MH / NIMH NIH HHS / United States
R34MH100356 / / National Institute of Mental Health / United States